Dr. Torsten Christ, Germany 

Dr. Bart Meuris, Belgium

Keywords: aortic root replacement; aortic stenosis; aortic valve replacement; Bentall; Valsalva graft

Although the majority of Bentall procedures have been performed with mechanical valves, the use of bioprosthetic valves is increasing. Modifications to the Bentall procedure may further enable the use of bioprosthetic valves: use of Valsalva pseudosinuses may reduce stress on the bioprosthetic leaflets and reduce the incidence of thromboembolism.

Chirichilli et al. routinely perform the Bentall procedure using the Valsalva graft with a Carpentier‑Edwards PERIMOUNT or PERIMOUNT Magna Ease valve. Here, they present the long‑term follow-up data assessing durability and valve-related complications.

Click on the link below to find out more about the performance of the PERIMOUNT valves combined with a modified Bentall procedure.  

Click here to access the full publication 

For professional use. For a listing of indications, contraindications, precautions, warnings, and potential adverse events, please refer to the Instructions for Use (consult eifu.edwards.com where applicable).

Edwards devices placed on the European market meeting the essential requirements referred to in Article 3 of the Medical Device Directive 93/42/EEC bear the CE marking of conformity.

Edwards, Edwards Lifesciences, the stylized E logo, Carpentier-Edwards, Magna, Magna Ease, PERI, PERIMOUNT and PERIMOUNT Magna are trademarks or service marks of Edwards Lifesciences Corporation or its affiliates. All other trademarks are the property of their respective owners.

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Keywords: aortic bioprostheses; aortic stenosis; aortic valve replacement

Surgical aortic valve replacement (SAVR) is still offered to elderly populations despite the potential for structural valve degeneration. Currently, however, there is limited comparative data on the long-term durability of different SAVR prostheses.

Reporting outcomes including repeat aortic valve replacement, prosthetic valve endocarditis and late all-cause mortality, Biancari et al. present key results from a retrospective, non-randomised, propensity-matched comparative analysis of the Trifecta and Carpentier-Edwards PERIMOUNT Magna Ease valves. The authors compared the outcomes of 2,216 patients who had undergone the procedure to implant one of the two SAVR prostheses.

Click the link below for an update on the latest research in aortic valve replacement.

Click here to access the full publication

For professional use. For a listing of indications, contraindications, precautions, warnings, and potential adverse events, please refer to the Instructions for Use (consult eifu.edwards.com where applicable).

Edwards devices placed on the European market meeting the essential requirements referred to in Article 3 of the Medical Device Directive 93/42/EEC bear the CE marking of conformity.

Edwards, Edwards Lifesciences, the stylized E logo, Carpentier-Edwards, Magna, Magna Ease, PERI, PERIMOUNT and PERIMOUNT Magna are trademarks of Edwards Lifesciences Corporation or its affiliates. All other trademarks or service marks are the property of their respective owners.

Keywords: aortic valve replacement; pericardial bioprostheses; reintervention

The use of pericardial bioprostheses in aortic valve replacement (AVR) is highly popular due to the lack of need for lifelong anticoagulation. Despite this, few studies have investigated the durability, rates of structural valve degeneration and valve-related events in newer bioprostheses. 

In this article Lam et al. present key results from a single-centre, retrospective study comparing three different aortic bioprosthetic valves . The authors assessed rates and causes of reinterventions in patients who underwent AVR with the Trifecta, Mitroflow and Carpentier-Edwards PERIMOUNT Magna Ease valves.

Follow the link below for the latest research in aortic valve replacement.

Click here to access the full publication

For professional use. For a listing of indications, contraindications, precautions, warnings, and potential adverse events, please refer to the Instructions for Use (consult eifu.edwards.com where applicable).

Edwards devices placed on the European market meeting the essential requirements referred to in Article 3 of the Medical Device Directive 93/42/EEC bear the CE marking of conformity.

Edwards, Edwards Lifesciences, the stylized E logo, Carpentier-Edwards, Magna, Magna Ease, PERI, PERIMOUNT, and PERIMOUNT Magna are trademarks or service marks of Edwards Lifesciences Corporation or its affiliates. All other trademarks are the property of their respective owners.

Keywords: bioprosthesis; aortic valve replacement; long-term outcomes; reintervention; mortality

Bioprostheses are the most common valve type used for aortic valve replacement (AVR) in the UK. Early structural valve degeneration of 19- to 21-mm Sorin Mitroflow LX valves led the UK Medicine and Healthcare products Regulatory Agency to issue a Medical Device Alert in 2017.

This summary presents key data from a single-centre, retrospective study comparing outcomes for the Mitroflow valve and the Carpentier-Edwards PERIMOUNT Magna valve. Theologou et al. analysed data from 2,608 patients, assessing aortic valve reintervention and mortality rates up to 10 years.

Download below to keep up to date with the latest research in AVR.

Click here to access the full publication

For professional use. For a listing of indications, contraindications, precautions, warnings, and potential adverse events, please refer to the Instructions for Use (consult eifu.edwards.com where applicable).

Edwards devices placed on the European market meet the requirements for bearing the CE marking of conformity.

Edwards, Edwards Lifesciences, the stylized E logo, Carpentier-Edwards, Magna, PERI, PERIMOUNT, and PERIMOUNT Magna are trademarks of Edwards Lifesciences Corporation or its affiliates. All other trademarks or service marks are the property of their respective owners.

Keywords: aortic bioprostheses; aortic valve replacement; structural valve degeneration

Long-term durability is a key concern for bioprosthetic valves, but measuring structural valve degeneration (SVD) has been complicated by different SVD definitions. The RESILIENCE trial is the first prospective study to use both clinical and imaging SVD definitions to assess long-term valve durability.

This summary describes the design of this multicentre, prospective trial. The trial will investigate predictors of durability and time to failure in RESILIA tissue valves, which are treated to minimise free aldehydes and preserve the tissue.

The trial will include up to 250 adults from up to 15 centres. The primary endpoint is time to valve failure due to SVD, while the secondary endpoints are valve leaflet calcification volume and SVD stage 2 or 3. Non‑contrast computed tomography and transthoracic echocardiography will be carried out at 5, 7, 9 and 11 years after valve implantation to assess valve morphology and haemodynamics.

Download below to keep up to date with the latest research in aortic valve replacement.

Click here to access the full publication

For professional use. For a listing of indications, contraindications, precautions, warnings, and potential adverse events, please refer to the Instructions for Use (consult eifu.edwards.com where applicable).

Edwards devices placed on the European market meet the requirements for bearing the CE marking of conformity.

Edwards, Edwards Lifesciences, the stylized E logo, Carpentier-Edwards, PERI, PERIMOUNT, and RESILIA are trademarks of Edwards Lifesciences Corporation or its affiliates. All other trademarks or service marks are the property of their respective owners.

EACTS Annual Meeting – Lisboa, October 2019