{"id":5406,"date":"2021-10-08T14:25:37","date_gmt":"2021-10-08T14:25:37","guid":{"rendered":"https:\/\/edwardseducation.com\/edwardsmasters\/?p=5406"},"modified":"2023-04-23T11:33:32","modified_gmt":"2023-04-23T11:33:32","slug":"mechanical-versus-bioprosthetic-valves-for-severe-aortic-stenosis","status":"publish","type":"post","link":"https:\/\/edwardseducation.com\/edwardsmasters\/mechanical-versus-bioprosthetic-valves-for-severe-aortic-stenosis\/","title":{"rendered":"Mechanical versus bioprosthetic valves for severe aortic stenosis"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"5406\" class=\"elementor elementor-5406\" data-elementor-post-type=\"post\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-4b815c0 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"4b815c0\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-5bdc28f\" data-id=\"5bdc28f\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-f82255d elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"f82255d\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-95d9486\" data-id=\"95d9486\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-8c2fc40 elementor-widget elementor-widget-text-editor\" data-id=\"8c2fc40\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>With the publication of the 2021 update to ESC\/EACTS guidelines for the management of valvular heart disease, new guidance\u00a0should be considered when caring for <strong>patients with severe\u00a0aortic stenosis<\/strong>.<sup>1\u00a0<\/sup><\/p><p>Three key recommendations stand out:<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-1e24d6e\" data-id=\"1e24d6e\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-9d7b321 elementor-widget elementor-widget-image\" data-id=\"9d7b321\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"1024\" height=\"231\" src=\"https:\/\/edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2021\/10\/07OCT21_web-page-text-font-9pt_0-4-1024x231.jpg\" class=\"attachment-large size-large wp-image-5663\" alt=\"\" srcset=\"https:\/\/edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2021\/10\/07OCT21_web-page-text-font-9pt_0-4-1024x231.jpg 1024w, https:\/\/edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2021\/10\/07OCT21_web-page-text-font-9pt_0-4-300x68.jpg 300w, https:\/\/edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2021\/10\/07OCT21_web-page-text-font-9pt_0-4-768x173.jpg 768w, https:\/\/edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2021\/10\/07OCT21_web-page-text-font-9pt_0-4.jpg 1076w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-874a0c1 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"874a0c1\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-abe5567\" data-id=\"abe5567\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-9032706 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"9032706\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-af261e3\" data-id=\"af261e3\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-d2e65bd elementor-widget elementor-widget-text-editor\" data-id=\"d2e65bd\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Early intervention is recommended for asymptomatic patients with a <strong>LVEF below 55%<\/strong> without another cause<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-2516147\" data-id=\"2516147\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-e4d65ed elementor-widget elementor-widget-image\" data-id=\"e4d65ed\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"1182\" height=\"1183\" src=\"https:\/\/edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2021\/10\/04OCT21_Stop-watch_0-1.jpg\" class=\"attachment-full size-full wp-image-5412\" alt=\"\" srcset=\"https:\/\/edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2021\/10\/04OCT21_Stop-watch_0-1.jpg 1182w, https:\/\/edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2021\/10\/04OCT21_Stop-watch_0-1-300x300.jpg 300w, https:\/\/edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2021\/10\/04OCT21_Stop-watch_0-1-1024x1024.jpg 1024w, https:\/\/edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2021\/10\/04OCT21_Stop-watch_0-1-150x150.jpg 150w, https:\/\/edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2021\/10\/04OCT21_Stop-watch_0-1-768x769.jpg 768w\" sizes=\"(max-width: 1182px) 100vw, 1182px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-8984386 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"8984386\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-2f31890\" data-id=\"2f31890\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-ee21a27 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"ee21a27\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-5edd4ad\" data-id=\"5edd4ad\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-0a80bd5 elementor-widget elementor-widget-text-editor\" data-id=\"0a80bd5\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>An emphasis on <strong>Heart Team collaboration<\/strong> to provide the optimal treatment while <strong>informing and involving patients<\/strong> in their decision-making<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-df6d116\" data-id=\"df6d116\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-6bbce79 elementor-widget elementor-widget-image\" data-id=\"6bbce79\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"1137\" height=\"1134\" src=\"https:\/\/edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2021\/09\/29SEPT21_Colaboration-icon_0-1.jpg\" class=\"attachment-full size-full wp-image-5374\" alt=\"\" srcset=\"https:\/\/edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2021\/09\/29SEPT21_Colaboration-icon_0-1.jpg 1137w, https:\/\/edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2021\/09\/29SEPT21_Colaboration-icon_0-1-300x300.jpg 300w, https:\/\/edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2021\/09\/29SEPT21_Colaboration-icon_0-1-1024x1021.jpg 1024w, https:\/\/edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2021\/09\/29SEPT21_Colaboration-icon_0-1-150x150.jpg 150w, https:\/\/edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2021\/09\/29SEPT21_Colaboration-icon_0-1-768x766.jpg 768w\" sizes=\"(max-width: 1137px) 100vw, 1137px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-529c058 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"529c058\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-7ed1640\" data-id=\"7ed1640\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-bd738b2 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"bd738b2\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-e502d24\" data-id=\"e502d24\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-f518ca0 elementor-widget elementor-widget-text-editor\" data-id=\"f518ca0\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>A clear age delineation that\u00a0<strong>patients younger than 75 years of age with<\/strong>\u00a0severe aortic stenosis\u00a0<strong>receive SAVR<\/strong>, and patients older receive TAVI<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-17ff149\" data-id=\"17ff149\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-4e70d55 elementor-widget elementor-widget-image\" data-id=\"4e70d55\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"218\" height=\"191\" src=\"https:\/\/edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2021\/09\/09SEPT21_People_0-1.png\" class=\"attachment-full size-full wp-image-5187\" alt=\"\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-517b53c elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"517b53c\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-a441226\" data-id=\"a441226\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-42e4716 elementor-widget elementor-widget-text-editor\" data-id=\"42e4716\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>It is established that the durability of modern surgical bioprosthetic valves is over 10 years,<sup>2<\/sup> and in recent years there has been a trend towards a greater use of bioprosthetic valves.<sup>3<\/sup> On the other hand, mechanical valves continue to be associated with bleeding risks because of the need for lifelong anticoagulation therapy, leading to lifestyle changes.<sup>4-6<\/sup><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-eed6aa1 elementor-section-full_width elementor-section-height-default elementor-section-height-default\" data-id=\"eed6aa1\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-0227ff5\" data-id=\"0227ff5\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-341de9b elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"341de9b\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-afc7773\" data-id=\"afc7773\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-436e627 elementor-widget elementor-widget-text-editor\" data-id=\"436e627\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Several large, long-term studies have demonstrated up to 20-year durability for the bioprosthetic Carpentier-Edwards PERIMOUNT <br \/>aortic valve.<sup>2,7,8<\/sup><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-f8591cc\" data-id=\"f8591cc\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-1755cd8 elementor-widget elementor-widget-image\" data-id=\"1755cd8\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t<figure class=\"wp-caption\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.edwards.com\/gb\/devices\/heart-valves\/aortic-pericardial\" target=\"_blank\">\n\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"476\" height=\"327\" src=\"https:\/\/edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2021\/10\/CE-PERIMOUNT_A1sw.png\" class=\"attachment-full size-full wp-image-5398\" alt=\"\" srcset=\"https:\/\/edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2021\/10\/CE-PERIMOUNT_A1sw.png 476w, https:\/\/edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2021\/10\/CE-PERIMOUNT_A1sw-300x206.png 300w\" sizes=\"(max-width: 476px) 100vw, 476px\" \/>\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<figcaption class=\"widget-image-caption wp-caption-text\"><\/figcaption>\n\t\t\t\t\t\t\t\t\t\t<\/figure>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<div class=\"elementor-element elementor-element-b6ad40c elementor-widget elementor-widget-text-editor\" data-id=\"b6ad40c\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p style=\"text-align: right\">Carpentier-Edwards PERIMOUNT valve<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-9031462 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"9031462\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-0eb2a42\" data-id=\"0eb2a42\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-450fedb elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"450fedb\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-b17935f\" data-id=\"b17935f\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-6e9f4fa elementor-widget elementor-widget-text-editor\" data-id=\"6e9f4fa\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>\u00a0<\/p><p>Two ongoing trials, COMMENCE and EU Feasibility, are evaluating the longevity of bioprosthetic aortic valves with novel RESILIA tissue after five-year implantation. Five-year results from these studies have demonstrated a favourable safety profile and good haemodynamic performance.<sup>9,10<\/sup><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-9ede08d\" data-id=\"9ede08d\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-c685add elementor-widget elementor-widget-image\" data-id=\"c685add\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t<figure class=\"wp-caption\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.edwards.com\/gb\/devices\/heart-valves\/aortic-pericardial\" target=\"_blank\">\n\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"233\" src=\"https:\/\/edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2021\/09\/inspiris_resilia_valve@2x-300x233.png\" class=\"attachment-medium size-medium wp-image-5347\" alt=\"\" srcset=\"https:\/\/edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2021\/09\/inspiris_resilia_valve@2x-300x233.png 300w, https:\/\/edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2021\/09\/inspiris_resilia_valve@2x.png 528w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/>\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<figcaption class=\"widget-image-caption wp-caption-text\"><\/figcaption>\n\t\t\t\t\t\t\t\t\t\t<\/figure>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<div class=\"elementor-element elementor-element-326ad69 elementor-widget elementor-widget-text-editor\" data-id=\"326ad69\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p style=\"text-align: right\">INSPIRIS RESILIA aortic valve<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-d019d3d elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"d019d3d\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-3d6cfd3\" data-id=\"3d6cfd3\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-2d90198 elementor-widget elementor-widget-text-editor\" data-id=\"2d90198\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Another study found that the INSPIRIS RESILIA valve reduced the length of hospital stay compared with mechanical valves (6.6 days <em>versus<\/em> 10.3 days).<sup>11\u00a0<\/sup><span style=\"font-family: MerriweatherSans;font-size: 1.14rem;font-weight: normal\">Selecting the right treatment for the patient requires many considerations, most importantly the desire of the informed patient.<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-9bf4857 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"9bf4857\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-1fbab7f\" data-id=\"1fbab7f\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-1b67233 elementor-widget elementor-widget-text-editor\" data-id=\"1b67233\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Additionally, the Heart Team needs to consider the age, estimated life expectancy, comorbidities, and anatomical and procedural characteristics of the patient; relative risks and long-term outcomes associated with SAVR or TAVI; prosthetic heart valve durability; feasibility of transfemoral TAVI; and local experience and outcome data to achieve optimal outcomes for patients.<sup>1<\/sup><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-c8c99bf elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"c8c99bf\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-a928a68\" data-id=\"a928a68\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-6573420 elementor-widget elementor-widget-heading\" data-id=\"6573420\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Recommended resources<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-eafcc44 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"eafcc44\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-no\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-99a7fe2\" data-id=\"99a7fe2\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-e5e7b90 elementor-widget elementor-widget-text-editor\" data-id=\"e5e7b90\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><blockquote class=\"wp-embedded-content\" data-secret=\"loRPNQaVmv\"><a href=\"https:\/\/edwardseducation.com\/edwardsmasters\/spavalve\/\">Biological versus mechanical prostheses for aortic valve replacement<\/a><\/blockquote><iframe class=\"wp-embedded-content\" sandbox=\"allow-scripts\" security=\"restricted\" style=\"position: absolute; clip: rect(1px, 1px, 1px, 1px);\" title=\"&#8220;Biological versus mechanical prostheses for aortic valve replacement&#8221; &#8212; Edwards Masters\" src=\"https:\/\/edwardseducation.com\/edwardsmasters\/spavalve\/embed\/#?secret=QYmS4bhBZW#?secret=loRPNQaVmv\" data-secret=\"loRPNQaVmv\" width=\"500\" height=\"282\" frameborder=\"0\" marginwidth=\"0\" marginheight=\"0\" scrolling=\"no\"><\/iframe><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-b87857d elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"b87857d\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-08b1a17\" data-id=\"08b1a17\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-7a31739 elementor-widget elementor-widget-heading\" data-id=\"7a31739\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">References<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-60ece62 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"60ece62\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-8229a53\" data-id=\"8229a53\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-4c54235 elementor-widget elementor-widget-text-editor\" data-id=\"4c54235\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>1. Vahanian A, Beyersdorf F, Praz F<i> et al.<\/i> 2021 ESC\/EACTS Guidelines for the management of valvular heart disease. <i>Eur Heart J<\/i>. 2021<b>:<\/b> doi:10.1093\/eurheartj\/ehab395.\n<p>2. Johnston DR, Soltesz EG, Vakil N<i> et al.<\/i> Long-term durability of bioprosthetic aortic valves: Implications from 12,569 implants. <i>Ann Thorac Surg<\/i>. 2015; <b>99:<\/b> 1239\u201347<\/p>\n<p>3. Bartus K, Sadowski J, Litwinowicz R<i> et al.<\/i> Changing trends in aortic valve procedures over the past ten years\u2014from mechanical prosthesis via stented bioprosthesis to TAVI procedures\u2014analysis of 50,846 aortic valve cases based on a Polish National Cardiac Surgery Database. <i>J Thorac Dis<\/i>. 2019; <b>11:<\/b> 2340\u20139.<\/p>\n<p>4. Head SJ, \u00c7elik M, Kappetein AP. Mechanical <i>versus <\/i>bioprosthetic aortic valve replacement. <i>Eur Heart J<\/i>. 2017; <b>38:<\/b> 2183\u201391.<\/p>\n<p>5.\u00a0Reul RM, Ramchandani MK, Reardon MJ. Transcatheter aortic valve-in-valve procedure in patients with bioprosthetic structural valve deterioration. <i>Methodist DeBakey Cardiovasc J<\/i>. 2017; <b>13:<\/b> 132.<\/p>\n<p>6.\u00a0Swinkels B, Ten Berg J, Kelder J<i> et al.<\/i> What can we learn from the past by means of very long-term follow-up after aortic valve replacement? <i>J Clin Med<\/i>. 2021; <b>10:<\/b> 3925.<\/p>\n<p>7. Bourguignon T, Bouquiaux-Stablo A-L, Candolfi P<i> et al.<\/i>Very long-term outcomes of the Carpentier-Edwards Perimount valve in aortic position. <i>Ann Thorac Surg<\/i>. 2015; <b>99:<\/b> 831\u20137.<\/p>\n<p>8. Forcillo J, Pellerin M, Perrault LP<i> et al.<\/i> Carpentier-Edwards pericardial valve in the aortic position: 25-years experience. <i>Ann Thorac Surg<\/i>. 2013; <b>96:<\/b> 486\u201393.<\/p>\n<p>9. Bartus K, Litwinowicz R, Bilewska A<i> et al.<\/i> Final 5-year outcomes following aortic valve replacement with a RESILIA\u2122 tissue bioprosthesis. <i>Eur J Cardio-Thorac Surg<\/i>. 2021; <b>59:<\/b> 434\u201341.<\/p>\n<p>10. Bavaria J, Griffith B, Heimansohn DA<i> et al.<\/i> Five-year outcomes of the COMMENCE trial investigating aortic valve replacement with a novel tissue bioprosthesis. Presented at the Society of Thoracic Surgeons (STS) Annual Meeting 2021.<\/p>\n<p>11. Meuris B. Innovation in anticalcification technology in heart valves leads to lower hospital stay in adults undergoing aortic valve replacement. Oral Presentation at HTAi 2021 virtual congress.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-eeb1608 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"eeb1608\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-no\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-7ee4471\" data-id=\"7ee4471\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-f8f848d elementor-widget elementor-widget-text-editor\" data-id=\"f8f848d\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><b>No clinical data are available that evaluate the long-term impact of RESILIA tissue in patients.<\/b><\/p><p><strong>For professional use. For a listing of indications, contraindications, precautions, warnings, and potential adverse events, please refer to the Instructions for Use (consult eifu.edwards.com where applicable).<\/strong><\/p><p><strong>Edwards devices placed on the European market meeting the essential requirements referred to in Article 3 of the Medical Device Directive 93\/42\/EEC bear the CE marking of conformity.<\/strong><\/p><p><b>Edwards, Edwards Lifesciences, the stylized E logo, Carpentier-Edwards, Carpentier-Edwards PERIMOUNT, COMMENCE, INSPIRIS, INSPIRIS RESILIA, PERIMOUNT, and RESILIA are trademarks or service marks of Edwards Lifesciences Corporation or its affiliates. All other trademarks are the property of their respective owners.<\/b><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-33b0e7f elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"33b0e7f\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-562ff2c\" data-id=\"562ff2c\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-a0c9d98 elementor-widget elementor-widget-text-editor\" data-id=\"a0c9d98\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>\u00a9 2021 Edwards Lifesciences Corporation. All rights reserved. PP&#8211;EU-2950 v1.0<\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-6c519d3 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"6c519d3\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-d209183\" data-id=\"d209183\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-dbc14ac elementor-widget elementor-widget-text-editor\" data-id=\"dbc14ac\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>Edwards Lifesciences<\/strong>\u00a0\u2022 Route de l\u2019Etraz 70, 1260 Nyon, Switzerland \u2022 edwards.com<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>With the publication of the 2021 update [&hellip;]<\/p>\n","protected":false},"author":26,"featured_media":7974,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"tags":[],"topic_interest":[450,449,442],"secondary_topic":[459,494,456,457,453],"article_tags":[532,563,585,652,1027,701,709,767,825,850],"anatomy":[],"topics":[],"course":[],"class_list":["post-5406","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry"],"acf":{"latestnews":false,"mostpopular":false,"views":"273","header__style":"default","header__alternative-title":"","footer-section__show":true,"footer-section__object":false,"slider__background-image":{"ID":7975,"id":7975,"title":"Big Size_Publications 01 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