{"id":2264,"date":"2020-03-26T11:07:30","date_gmt":"2020-03-26T11:07:30","guid":{"rendered":"https:\/\/edwardseducation.com\/edwardsmasters\/?p=2264"},"modified":"2023-04-23T12:54:58","modified_gmt":"2023-04-23T12:54:58","slug":"resilience-trial-study-design-evaluating-the-durability-of-resilia-tissue-valves-in-subjects-under-65-years-old","status":"publish","type":"post","link":"https:\/\/edwardseducation.com\/edwardsmasters\/resilience-trial-study-design-evaluating-the-durability-of-resilia-tissue-valves-in-subjects-under-65-years-old\/","title":{"rendered":"RESILIENCE trial study design: evaluating the durability of RESILIA tissue valves in subjects under 65 years old"},"content":{"rendered":"\n

Keywords<\/strong>: aortic bioprostheses; aortic valve replacement; structural valve degeneration<\/p>\n\n\n\n

Long-term durability is a key concern for bioprosthetic\nvalves, but measuring structural valve degeneration (SVD) has been complicated\nby different SVD definitions. The RESILIENCE trial is the first prospective\nstudy to use both clinical and imaging SVD definitions to assess long-term valve\ndurability.<\/p>\n\n\n\n

This summary describes the design of this multicentre, prospective trial. The\ntrial will investigate predictors of durability and time to failure in RESILIA\ntissue valves, which are treated to minimise free aldehydes and preserve the\ntissue.<\/p>\n\n\n\n

The trial will include up to 250 adults from up to 15\ncentres. The primary endpoint is time to valve failure due to SVD, while the\nsecondary endpoints are valve leaflet calcification volume and SVD stage 2 or 3.\nNon\u2011contrast computed tomography and transthoracic echocardiography will be\ncarried out at 5, 7, 9 and 11 years after valve implantation to assess\nvalve morphology and haemodynamics.<\/p>\n\n\n\n

Download below to keep up to date with the latest research\nin aortic valve replacement.<\/p>\n\n\n\n

Click\nhere to access the full publication<\/a><\/p>\n\n\n\n

For professional use. <\/strong>For a\nlisting of indications, contraindications, precautions, warnings, and potential\nadverse events, please refer to the Instructions for Use (consult\neifu.edwards.com where applicable).<\/p>\n\n\n\n

Edwards devices placed on the\nEuropean market meet the requirements for bearing the CE marking of conformity.<\/p>\n\n\n\n

Edwards, Edwards Lifesciences, the\nstylized E logo, Carpentier-Edwards, PERI, PERIMOUNT, and RESILIA are\ntrademarks of Edwards Lifesciences Corporation or its affiliates. All other\ntrademarks or service marks are the property of their respective owners.<\/p>\n\n\n\n

Summary – PPT<\/a>Download<\/a><\/div>\n\n\n\n
Summary – PDF<\/a>Download<\/a><\/div>\n","protected":false},"excerpt":{"rendered":"

Keywords: aortic bioprostheses; aortic valve replacement; structural 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trial study design: evaluating the durability of RESILIA tissue valves in subjects under 65 years old - Edwards Masters<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/edwardseducation.com\/edwardsmasters\/resilience-trial-study-design-evaluating-the-durability-of-resilia-tissue-valves-in-subjects-under-65-years-old\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"RESILIENCE trial study design: evaluating the durability of RESILIA tissue valves in subjects under 65 years old - Edwards Masters\" \/>\n<meta property=\"og:description\" content=\"Keywords: aortic bioprostheses; aortic valve replacement; structural […]\" \/>\n<meta property=\"og:url\" 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