{"id":10523,"date":"2023-11-02T10:39:34","date_gmt":"2023-11-02T10:39:34","guid":{"rendered":"https:\/\/edwardseducation.com\/edwardsmasters\/?p=10523"},"modified":"2023-11-15T12:40:42","modified_gmt":"2023-11-15T12:40:42","slug":"clinical-performance-of-a-novel-bioprosthetic-surgical-aortic-valve-in-a-german-high-volume-center","status":"publish","type":"post","link":"https:\/\/edwardseducation.com\/edwardsmasters\/clinical-performance-of-a-novel-bioprosthetic-surgical-aortic-valve-in-a-german-high-volume-center\/","title":{"rendered":"Clinical performance of a novel bioprosthetic surgical aortic valve in a German high-volume center"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"10523\" class=\"elementor elementor-10523\" data-elementor-post-type=\"post\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-7d2deee elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"7d2deee\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-aa51d81\" data-id=\"aa51d81\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-a5955bc elementor-widget elementor-widget-text-editor\" data-id=\"a5955bc\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>El-Sayed Ahmad A, Giammarino S, Salamate S, Fehske W, Sirat S, Amer M, Bramlage P, Bakhtiary F and Doss M.<\/p><p><em>Journal of Cardiac Surgery. <\/em>2022; 37: 4833\u201340<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-e1a280d elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"e1a280d\" data-element_type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-4d3a29a\" data-id=\"4d3a29a\" data-element_type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-1253f27 elementor-widget elementor-widget-heading\" data-id=\"1253f27\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Key points:<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-9b6fd18 elementor-widget elementor-widget-text-editor\" data-id=\"9b6fd18\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ul><li>The mid-term follow-up results of this single- centre study, in a patient population with a mean age of 56.8 years, indicate favourable procedural outcomes, with adequate durability and no cases of structural valve deterioration (SVD).<\/li><li>At Year 3, haemodynamic performance was stable and adequate.<\/li><li>INSPIRIS RESILIA aortic valve may represent a bioprosthesis suitable for younger patients, giving excellent results.\u00a0<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-3a2499b elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"3a2499b\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-8626ca7\" data-id=\"8626ca7\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-835e893 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"835e893\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-0677840\" data-id=\"0677840\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-d0c49aa elementor-widget elementor-widget-heading\" data-id=\"d0c49aa\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Background information<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-fc24865 elementor-widget elementor-widget-text-editor\" data-id=\"fc24865\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ul><li>Surgical aortic valve replacement (SAVR) using bioprosthetic valves is becoming increasingly popular in younger patients.<\/li><li>The INSPIRIS RESILIA aortic valve features a tri-leaflet bovine pericardial tissue mounted under a flexible frame and has been developed to reduce calcification, therefore, increasing durability.\u00a0<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-615d509 elementor-widget elementor-widget-heading\" data-id=\"615d509\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Aim<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-279e017 elementor-widget elementor-widget-text-editor\" data-id=\"279e017\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ul><li>To analyse mid-term follow-up data in patients who underwent SAVR with an INSPIRIS RESILIA bioprosthetic heart valve at the Heart Centre in Siegberg-Wuppertal.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5543502 elementor-widget elementor-widget-heading\" data-id=\"5543502\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Type of study<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-9e3b73d elementor-widget elementor-widget-text-editor\" data-id=\"9e3b73d\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ul><li>A single-centre, non- randomised retrospective study.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c0e1881 elementor-widget elementor-widget-heading\" data-id=\"c0e1881\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Endpoints<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2295d4f elementor-widget elementor-widget-text-editor\" data-id=\"2295d4f\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ul><li>The primary endpoint was the haemodynamic properties of the RESILIA tissue valve at mid-term follow-up.<\/li><li>Secondary objectives included mortality and valve-related complications (according to Valve Academic Research Consortium-3 criteria).<sup>1<\/sup><\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-face0a1 elementor-widget elementor-widget-heading\" data-id=\"face0a1\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Limitations<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-9468357 elementor-widget elementor-widget-text-editor\" data-id=\"9468357\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ul><li>This is a retrospective, non- randomised, single-centre study with a small sample size and no control group.\u00a0<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-0ad4a22 elementor-widget elementor-widget-heading\" data-id=\"0ad4a22\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Methods<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3747117 elementor-widget elementor-widget-text-editor\" data-id=\"3747117\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ul><li>All patients with aortic valve disease who received an INSPIRIS RESILIA aortic valve between April 2017 and December 2019 at the Division of Cardiac Surgery, Heart Centre Siegberg-Wuppertal, University Witten- Herdecke, Germany (n=154) were included.<\/li><li>Follow-up data were\u00a0 collected in the clinic or by telephone during the 3-month closing interval ending in April 2021.\u00a0<\/li><li>Echocardiographic data were collected twice a year.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-cbf1251\" data-id=\"cbf1251\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-6fc3bd0 elementor-widget elementor-widget-heading\" data-id=\"6fc3bd0\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Results<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-61cdbfd elementor-widget elementor-widget-text-editor\" data-id=\"61cdbfd\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><b>Study population<\/b><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-07b67e3 elementor-widget elementor-widget-text-editor\" data-id=\"07b67e3\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ul><li>Mean (\u00b1 standard deviation) patient follow-up was 2.05 \u00b1 0.77 years.<\/li><li>Baseline characteristics are listed in Table 1.\u00a0<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1f8e899 elementor-widget elementor-widget-text-editor\" data-id=\"1f8e899\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><b>Mortality and valve-related complications<\/b><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-47997e0 elementor-widget elementor-widget-text-editor\" data-id=\"47997e0\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ul><li>30-day, 1-year and 3-year freedom from mortality were 98.7%, 97.3% and 87.7%, respectively; the rate of valve-related mortality was 0%.\u00a0<\/li><li>There were no cases of SVD or valve-related thrombosis and one (0.6%) case of reoperation due to endocarditis.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4223b0d elementor-widget elementor-widget-text-editor\" data-id=\"4223b0d\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><b>Table 1: Patient baseline characteristics<\/b><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-d932d7a elementor-widget elementor-widget-image\" data-id=\"d932d7a\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"438\" height=\"349\" src=\"https:\/\/edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2023\/11\/clinical-tb-1.png\" class=\"attachment-large size-large wp-image-10552\" alt=\"\" srcset=\"https:\/\/edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2023\/11\/clinical-tb-1.png 438w, https:\/\/edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2023\/11\/clinical-tb-1-300x239.png 300w\" sizes=\"(max-width: 438px) 100vw, 438px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-de6fc40 elementor-widget elementor-widget-text-editor\" data-id=\"de6fc40\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><b>Haemodynamic properties<\/b><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-143e03a elementor-widget elementor-widget-text-editor\" data-id=\"143e03a\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ul>\n \t<li>At last follow-up:<\/br>\u2013 Effective orifice area was 1.9 cm<sup>2<\/sup>.<\/br>\n\u2013 Peak gradient was 23.6 mmHg. <\/br>\n\u2013 Mean gradient was 13.9 mmHg.<\/li>\n<li>Figure 1 shows peak and mean gradients at 3-year follow-up by valve size.<\/li>\n<\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2c2715d elementor-widget elementor-widget-text-editor\" data-id=\"2c2715d\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><b>Figure 1: Peak and mean gradients at 3-year follow-up for each valve size<\/b><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-0ec991d elementor-widget elementor-widget-image\" data-id=\"0ec991d\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"432\" height=\"355\" src=\"https:\/\/edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2023\/11\/clinical-tb2.png\" class=\"attachment-large size-large wp-image-10562\" alt=\"\" srcset=\"https:\/\/edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2023\/11\/clinical-tb2.png 432w, https:\/\/edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2023\/11\/clinical-tb2-300x247.png 300w\" sizes=\"(max-width: 432px) 100vw, 432px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ed92991 elementor-widget elementor-widget-heading\" data-id=\"ed92991\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Conclusions<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-406d8e3 elementor-widget elementor-widget-text-editor\" data-id=\"406d8e3\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ul><li>The INSPIRIS RESILIA valve shows adequate mid-term durability and haemodynamic performance.<\/li><li>Further studies are required to assess long-term durability and efficacy, especially in younger patients.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4fccce7 elementor-widget elementor-widget-heading\" data-id=\"4fccce7\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Reference<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c988f59 elementor-widget elementor-widget-text-editor\" data-id=\"c988f59\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ol><li>Genereux P, Piazza N, Alu MC et al. Valve Academic Research Consortium 3: Updated endpoint definitions for aortic valve clinical research. <br \/><em>Eur Heart J.<\/em> 2021; <strong>42:<\/strong> 1825\u201357<\/li><\/ol>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-8fa4320 elementor-widget elementor-widget-text-editor\" data-id=\"8fa4320\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><em>This document is a summary of the El-Sayed Ahmed A <\/em><em>et al. paper and covers key information including aim, <\/em><em>type of study, methods, results and conclusions.<\/em><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2c4baef elementor-widget elementor-widget-text-editor\" data-id=\"2c4baef\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>The full abstract is available at:<\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c1475a2 elementor-widget elementor-widget-text-editor\" data-id=\"c1475a2\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1111\/jocs.17198\"><strong>doi: 10.1111\/jocs.17198<\/strong><\/a><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e16e77b elementor-widget elementor-widget-heading\" data-id=\"e16e77b\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Abbreviations<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-12a2247 elementor-widget elementor-widget-image\" data-id=\"12a2247\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"404\" height=\"156\" src=\"https:\/\/edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2023\/11\/abbrclinicl.png\" class=\"attachment-large size-large wp-image-10572\" alt=\"\" srcset=\"https:\/\/edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2023\/11\/abbrclinicl.png 404w, https:\/\/edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2023\/11\/abbrclinicl-300x116.png 300w\" sizes=\"(max-width: 404px) 100vw, 404px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-dbe079e elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"dbe079e\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-34a8baa\" data-id=\"34a8baa\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-1c42da2 elementor-widget elementor-widget-text-editor\" data-id=\"1c42da2\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>No clinical data are available that evaluate the long-term impact of RESILIA tissue in patients.\u00a0<\/p><p><strong>Medical<\/strong> <strong>device<\/strong> <strong>for<\/strong> <strong>professional<\/strong> <strong>use.<\/strong> <strong>For<\/strong> <strong>a<\/strong> <strong>listing<\/strong> <strong>of<\/strong> <strong>indications,<\/strong> <strong>contraindications,<\/strong> <strong>precautions,<\/strong> <strong>warnings,<\/strong> <strong>and<\/strong> <strong>potential<\/strong><strong> adverse events, please refer to the Instructions for Use (consult eifu.edwards.com where applicable).<\/strong><\/p><p>Edwards, Edwards Lifesciences, the stylized E logo, Carpentier-Edwards, Carpentier-Edwards PERIMOUNT, Carpentier-Edwards PERIMOUNT Magna Ease, Magna, Magna Ease, PERI, PERIMOUNT and PERIMOUNT Magna are trademarks or service marks of Edwards Lifesciences Corporation. All other trademarks are the property of their respective owners.<\/p><p>\u00a9 2023 Edwards Lifesciences Corporation. All rights reserved. PP&#8211;EU-6062 v1.0<\/p><p><strong>Edwards Lifesciences \u2022<\/strong> Route de l\u2019Etraz 70, 1260 Nyon, Switzerland \u2022 edwards.com<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>El-Sayed Ahmad A, Giammarino S, Salamate S, [&hellip;]<\/p>\n","protected":false},"author":1502,"featured_media":10926,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"tags":[],"topic_interest":[],"secondary_topic":[],"article_tags":[],"anatomy":[],"topics":[],"course":[],"class_list":["post-10523","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry"],"acf":{"MobileLandscapeImage":{"ID":10931,"id":10931,"title":"Clinical summary El-sayed 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This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Clinical performance of a novel bioprosthetic surgical aortic valve in a German high-volume center - Edwards Masters<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/edwardseducation.com\/edwardsmasters\/clinical-performance-of-a-novel-bioprosthetic-surgical-aortic-valve-in-a-german-high-volume-center\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Clinical performance of a novel bioprosthetic surgical aortic valve in a German high-volume center - Edwards Masters\" \/>\n<meta property=\"og:description\" content=\"El-Sayed Ahmad A, Giammarino S, Salamate S, [&hellip;]\" \/>\n<meta property=\"og:url\" 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