{"id":10465,"date":"2023-11-02T10:35:18","date_gmt":"2023-11-02T10:35:18","guid":{"rendered":"https:\/\/edwardseducation.com\/edwardsmasters\/?p=10465"},"modified":"2023-11-14T11:59:09","modified_gmt":"2023-11-14T11:59:09","slug":"perimount-magna-ease-vs-inspiris-resilia-valve-a-ps-matched-analysis-of-the-hemodynamic-performances-in-patients-below-70-years-of-age","status":"publish","type":"post","link":"https:\/\/edwardseducation.com\/edwardsmasters\/perimount-magna-ease-vs-inspiris-resilia-valve-a-ps-matched-analysis-of-the-hemodynamic-performances-in-patients-below-70-years-of-age\/","title":{"rendered":"PERIMOUNT Magna Ease vs INSPIRIS RESILIA valve: A PS-matched analysis of the hemodynamic performances in patients below 70 years of age"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"10465\" class=\"elementor elementor-10465\" data-elementor-post-type=\"post\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-2f653a8 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"2f653a8\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-74e5244\" data-id=\"74e5244\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-1bf4712 elementor-widget elementor-widget-text-editor\" data-id=\"1bf4712\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Francica A, Tonelli F, Rossetti C, Galeone A, Perrone F, Luciani GB and Onorati F.<\/p><p><em>Journal of Clinical Medicine. 2023; 12: 2077.<\/em><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-7ccf93c elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"7ccf93c\" data-element_type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-eb0a6db\" data-id=\"eb0a6db\" data-element_type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-cf8e501 elementor-widget elementor-widget-heading\" data-id=\"cf8e501\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Key points<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-50a6cae elementor-widget elementor-widget-text-editor\" data-id=\"50a6cae\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ul><li>\u00a0This is the first propensity-matched analysis comparing the haemodynamic performance of the INSPIRIS RESILIA valve with the Carpentier-Edwards PERIMOUNT Magna Ease valve at mid-term follow-up in patients under 70 years of age.<\/li><li>\u00a0For up to 3 years post surgery, the haemodynamic performance was comparable between the two valve types in this patient population; however, the INSPIRIS RESILIA valve was associated with lower intraventricular septum thickness measurements and systolic pulmonary artery pressure.\u00a0<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-96096f7 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"96096f7\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-2bea3e46\" data-id=\"2bea3e46\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-25dbae83 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"25dbae83\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-377173d8\" data-id=\"377173d8\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-3caeebb5 elementor-widget elementor-widget-heading\" data-id=\"3caeebb5\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Background information<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-158d5eb elementor-widget elementor-widget-text-editor\" data-id=\"158d5eb\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ul>\n \t<li>The PERIMOUNT Magna Ease valve has been implanted worldwide during the last 10 years and has achieved excellent long- erm clinical and haemodynamic outcomes.<\/li>\n \t<li>The INSPIRIS RESILIA\u00a0 valve was introduced\u00a0 with the aim of\u00a0 improving valve\u00a0 durability by reducing calcification; <sup>1<\/sup> but how\u00a0 the haemodynamics of\u00a0 this valve compare with\u00a0 the PERIMOUNT Magna Ease valve has\u00a0 not\u00a0 previously been\u00a0 evaluated.<\/li>\n<\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-58c09d50 elementor-widget elementor-widget-heading\" data-id=\"58c09d50\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Aim<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4633fd elementor-widget elementor-widget-text-editor\" data-id=\"4633fd\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ul><li>To compare the\u00a0 haemodynamic performance of the PERIMOUNT Magna Ease valve with the\u00a0 INSPIRIS RESILIA valve in patients under 70 years.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-31529a99 elementor-widget elementor-widget-heading\" data-id=\"31529a99\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Type of study<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-30a88e35 elementor-widget elementor-widget-text-editor\" data-id=\"30a88e35\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ul><li>A retrospective single-centre study with propensity-matched analysis.\u00a0<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2d91f264 elementor-widget elementor-widget-heading\" data-id=\"2d91f264\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Endpoints<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-72e14e12 elementor-widget elementor-widget-text-editor\" data-id=\"72e14e12\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ul><li>The primary endpoint was to compare the short- and mid-term haemodynamic performances of the PERIMOUNT Magna Ease valve and the INSPIRIS RESILIA valve.<\/li><li>Secondary endpoints included:<br \/>\u2013 Haemodynamic performance stratified by prosthetic valve size. <br \/>\u2013 Postoperative outcomes.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-560da928 elementor-widget elementor-widget-heading\" data-id=\"560da928\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Results<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-8cba7d1 elementor-widget elementor-widget-text-editor\" data-id=\"8cba7d1\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><b>Baseline characteristics<\/b><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-193eb4ef elementor-widget elementor-widget-text-editor\" data-id=\"193eb4ef\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ul><li>The two propensity score-matched populations were similar in age (mean 57.4 \u00b1 10.1 years) and risk profile (EuroSCORE II 2.7 \u00b1 2.4%).<\/li><li>The most common comorbidity was hypertension (54.5%), and 31.6% of patients were in New York Heart Association functional class III or IV.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4a504d1 elementor-widget elementor-widget-text-editor\" data-id=\"4a504d1\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><b>Postoperative outcomes<\/b><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-bc97a53 elementor-widget elementor-widget-text-editor\" data-id=\"bc97a53\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ul><li>Postoperative outcomes were comparable between the two populations.<\/li><li>The overall incidence of major complications was low:<br \/>\u2013 No procedural or periprocedural mortality.<p>\u2013 Permanent pacemaker implantation: 3.3% PERIMOUNT Magna Ease valve versus 1.6% INSPIRIS RESILIA valve (p=0.4).<br \/>\u2013 Type 1 stroke: 0.8% in both groups.\u00a0<br \/>\u2013 Paroxysmal atrial fibrillation was the most common complication (22.1% PERIMOUNT Magna Ease valve vs 24.6% INSPIRIS RESILIA valve, p=0.88).<\/p><\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-18359da elementor-widget elementor-widget-text-editor\" data-id=\"18359da\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><b>Haemodynamic performance<\/b><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-9d0f77f elementor-widget elementor-widget-text-editor\" data-id=\"9d0f77f\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ul><li>PERIMOUNT Magna Ease valve and INSPIRIS RESILIA valve showed similar haemodynamic performance at 1-year and 3-year follow-up in terms of peak and mean gradient (Figure 1) and left ventricular volumes and diameters.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-d3ff2eb\" data-id=\"d3ff2eb\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-7b89caa3 elementor-widget elementor-widget-heading\" data-id=\"7b89caa3\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Methods<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-16dc9073 elementor-widget elementor-widget-text-editor\" data-id=\"16dc9073\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ul><li>The study population consisted of patients who were aged between 18 and 70 years and underwent aortic valve replacement (AVR) at the Division of Cardiac Surgery, University of Verona.<p>\u2013 Between January 2010 and December 2012, 238 patients underwent AVR with a PERIMOUNT Magna Ease valve.\u00a0<br \/>\u2013 Between September 2017 and January 2022, 192 patients underwent AVR with an INSPIRIS RESILIA valve.<\/p><\/li><li><p>A propensity score-matched analysis was performed to account for baseline differences, resulting in 122 matched pairs.<\/p><\/li><li><p>Echocardiographic data was collected 1 and 3 years post surgery.<\/p><\/li><li><p>At 1 year, patients with INSPIRIS RESILIA valves had lower intraventricular septum thickness measurements (12.1 \u00b1 2.0 mm vs 13.2 \u00b1 2.1 mm, p=0.011) and systolic pulmonary artery pressure (26.8 \u00b1 7.6 mmHg vs 34.3 \u00b1 9.3 mmHg, p=0.001) than those with PERIMOUNT Magna Ease valves.<\/p><\/li><li><p>Severe structural valve deterioration occurred in four patients (all &lt;50 years old) with PERIMOUNT Magna Ease valve and no patients with INSPIRIS RESILIA valve.<\/p><\/li><li><p>When stratified by valve size, there were no differences in haemodynamic behaviour between the two valves for any valve size category.<\/p><\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7feb9b8 elementor-widget elementor-widget-heading\" data-id=\"7feb9b8\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Limitations<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-fd69ddd elementor-widget elementor-widget-text-editor\" data-id=\"fd69ddd\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ul><li>This was a retrospective study.<\/li><li>The two patient groups were treated almost 10 years apart, and patients with INSPIRIS RESILIA valves had a shorter follow-up.<\/li><li>There was no standardised protocol for echocardiography, although all labs complied with guidelines.<\/li><li>Data retrieval was challenging due to the study taking place during the COVID-19 pandemic.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-8e9c447 elementor-widget elementor-widget-heading\" data-id=\"8e9c447\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Conclusion<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7cae08c elementor-widget elementor-widget-text-editor\" data-id=\"7cae08c\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ul><li>The INSPIRIS RESILIA valve achieved the same efficacy and safety outcomes as the PERIMOUNT Magna Ease valve at mid-term follow-up in this propensity-matched analysis of patients under 70 years of age.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-49837ab elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"49837ab\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-829b51a\" data-id=\"829b51a\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-e50e304 elementor-widget elementor-widget-image\" data-id=\"e50e304\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"604\" height=\"1024\" src=\"https:\/\/edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2023\/11\/article-chart-604x1024.png\" class=\"attachment-large size-large wp-image-10634\" alt=\"\" srcset=\"https:\/\/edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2023\/11\/article-chart-604x1024.png 604w, https:\/\/edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2023\/11\/article-chart-177x300.png 177w, https:\/\/edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2023\/11\/article-chart-768x1302.png 768w, https:\/\/edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2023\/11\/article-chart.png 782w\" sizes=\"(max-width: 604px) 100vw, 604px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-0511070 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"0511070\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-7cd8a42\" data-id=\"7cd8a42\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-ed3f132 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"ed3f132\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-c74ac94\" data-id=\"c74ac94\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-190af2d elementor-widget elementor-widget-heading\" data-id=\"190af2d\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Reference<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-05c1cdb elementor-widget elementor-widget-text-editor\" data-id=\"05c1cdb\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ol><li>Flameng W, Hermans H, Verbeken E et al.<br \/>A randomized assessment of an advanced tissue preservation technology in the juvenile sheep model. J Thorac Cardiovasc Surg. 2015; <strong>149<\/strong>: 340\u20135.<\/li><\/ol>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b6fd2cd elementor-widget elementor-widget-text-editor\" data-id=\"b6fd2cd\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><em>This document is a summary of the Francica A et al. <\/em><em>paper and covers key information including aim, <\/em><em>type of study, methods, results and conclusion.\u00a0<\/em><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-fa3c66b elementor-widget elementor-widget-text-editor\" data-id=\"fa3c66b\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><b>The full pubblication is available at:<\/b><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4c68479 elementor-widget elementor-widget-text-editor\" data-id=\"4c68479\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><a href=\"https:\/\/www.mdpi.com\/2077-0383\/12\/5\/2077\"><em><strong>doi: 10.3390\/jcm12052077<\/strong><\/em><\/a><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b32d6e9 elementor-widget elementor-widget-heading\" data-id=\"b32d6e9\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Abbreviations<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-564da30 elementor-widget elementor-widget-image\" data-id=\"564da30\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"362\" height=\"112\" src=\"https:\/\/edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2023\/11\/abbrperi.png\" class=\"attachment-large size-large wp-image-10516\" alt=\"\" srcset=\"https:\/\/edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2023\/11\/abbrperi.png 362w, https:\/\/edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2023\/11\/abbrperi-300x93.png 300w\" sizes=\"(max-width: 362px) 100vw, 362px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-a91f60f\" data-id=\"a91f60f\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-92c842d elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"92c842d\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-4f0dfb1\" data-id=\"4f0dfb1\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-b7b44b4 elementor-widget elementor-widget-text-editor\" data-id=\"b7b44b4\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>No clinical data are available that evaluate the long-term impact of RESILIA tissue in patients.\u00a0<\/strong><\/p><p><strong>Medical<\/strong> <strong>device<\/strong> <strong>for<\/strong> <strong>professional<\/strong> <strong>use.<\/strong> <strong>For<\/strong> <strong>a<\/strong> <strong>listing<\/strong> <strong>of<\/strong> <strong>indications,<\/strong> <strong>contraindications,<\/strong> <strong>precautions,<\/strong> <strong>warnings,<\/strong> <strong>and<\/strong> <strong>potential<\/strong><strong> adverse events, please refer to the Instructions for Use (consult eifu.edwards.com where applicable).<\/strong><\/p><p>Edwards, Edwards Lifesciences, the stylized E logo, Carpentier-Edwards, Carpentier-Edwards PERIMOUNT, Carpentier-Edwards PERIMOUNT Magna Ease, Magna, Magna Ease, PERI, PERIMOUNT and PERIMOUNT Magna are trademarks or service marks of Edwards Lifesciences Corporation. All other trademarks are the property of their respective owners.<\/p><p>\u00a9 2023 Edwards Lifesciences Corporation. All rights reserved. PP&#8211;EU-6466 v1.0<\/p><p><strong>Edwards Lifesciences \u2022<\/strong> Route de l\u2019Etraz 70, 1260 Nyon, Switzerland \u2022 edwards.com<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Francica A, Tonelli F, Rossetti C, Galeone [&hellip;]<\/p>\n","protected":false},"author":1502,"featured_media":10752,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"tags":[],"topic_interest":[],"secondary_topic":[],"article_tags":[],"anatomy":[],"topics":[],"course":[],"class_list":["post-10465","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry"],"acf":{"views":"120","MobileLandscapeImage":{"ID":10753,"id":10753,"title":"Clinical summary_Francica_2 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This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>PERIMOUNT Magna Ease vs INSPIRIS RESILIA valve: A PS-matched analysis of the hemodynamic performances in patients below 70 years of age - Edwards Masters<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/edwardseducation.com\/edwardsmasters\/perimount-magna-ease-vs-inspiris-resilia-valve-a-ps-matched-analysis-of-the-hemodynamic-performances-in-patients-below-70-years-of-age\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"PERIMOUNT Magna Ease vs INSPIRIS RESILIA valve: A PS-matched analysis of the hemodynamic performances in patients below 70 years of age - Edwards Masters\" \/>\n<meta property=\"og:description\" content=\"Francica A, Tonelli F, Rossetti C, Galeone [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/edwardseducation.com\/edwardsmasters\/perimount-magna-ease-vs-inspiris-resilia-valve-a-ps-matched-analysis-of-the-hemodynamic-performances-in-patients-below-70-years-of-age\/\" \/>\n<meta property=\"og:site_name\" content=\"Edwards Masters\" \/>\n<meta property=\"article:published_time\" content=\"2023-11-02T10:35:18+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-11-14T11:59:09+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/edwardseducation.com\/edwardsmasters\/wp-content\/uploads\/sites\/2\/2023\/11\/Clinical-summary_Francica_2-400\u00d7265.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"400\" \/>\n\t<meta property=\"og:image:height\" content=\"265\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Todd Edelman\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta 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